Publikacje
2022
Antoszczak M., Otto-Ślusarczyk D., Kordylas M., Struga M., Huczyński A. Synthesis of Lasalocid-Based Bioconjugates and Evaluation of Their Anticancer Activity. ACS Omega, 2022, 7 (2), 1943-1955.
Chrzanowska A., Olejarz W., Kubiak-Tomaszewska G., Ciechanowicz A.K., Struga M. The Effect of Fatty Acids on Ciprofloxacin Cytotoxic Activity in Prostate Cancer Cell Lines—Does Lipid Component Enhance Anticancer Ciprofloxacin Potential? Cancers, 2022, 14 (2), art. no. 409, .
Kubiak-Tomaszewska G., Roszkowski P., Grosicka-Maciąg E., Strzyga-Łach P., Struga M. Effect of Hydroxyl Groups Esterification with Fatty Acids on the Cytotoxicity and Antioxidant Activity of Flavones. Molecules, 2022, 27 (2), 420.
Roszkowski P., Szymańska‐Majchrzak J., Koliński M., Kmiecik S., Wrzosek M., Struga M., Szulczyk D. Novel tetrazole‐based antimicrobial agents targeting clinical bacteria strains: Exploring the inhibition of staphylococcus aureus dna topoisomerase iv and gyrase. International Journal of Molecular Sciences, 2022, 23 (1), 378.
Grodner B., Napiórkowska M., Pisklak D.M. In vitro and in silico kinetic studies of patented 1,7‐diethyl and 1,7‐dimethyl aminoalkanol derivatives as new inhibitors of acetylcholinesterase. International Journal of Molecular Sciences, 2022, 23 (1), 270.
2021
Grodner B., Napiórkowska M., Pisklak D.M. Kinetic studies of newly patented aminoalkanol derivatives with potential anticancer activity as competitive inhibitors of prostate acid phosphatase (2021) International Journal of Molecular Sciences, 22 (21), 11761.
Cieślak M., Napiórkowska M., Kaźmierczak‐Barańska J., Królewska‐Golińska K., Hawrył A., Wybrańska I., Nawrot, B. New succinimides with potent anticancer activity: Synthesis, activation of stress signaling pathways and characterization of apoptosis in leukemia and cervical cancer cells (2021) International Journal of Molecular Sciences, 22 (9), 4318.
Grodner B., Napiórkowska M. Dual 2-hydroxypropyl-β-cyclodextrin and 5,10,15,20-tetrakis (4-hydroxyphenyl) porphyrin system as a novel Chiral-Achiral selector complex for enantioseparation of Aminoalkanol derivatives with anticancer activity in capillary electrophoresis. Molecules, 2021, 26 (4), 993.
Chrzanowska A., Drzewiecka‐Antonik A., Dobrzyńska K., Stefańska J., Pietrzyk P., Struga M., Bielenica A. The cytotoxic effect of copper (Ii) complexes with halogenated 1,3‐disubstituted arylthioureas on cancer and bacterial cells. International Journal of Molecular Sciences, 2021, 22 (21), 11415.
Czerwonka D., Mielczarek-Puta M., Antoszczak M., Cioch A., Struga M., Huczyński A. Evaluation of the anticancer activity of singly and doubly modified analogues of C20-epi-salinomycin. European Journal of Pharmacology, 2021, 908, 174347.
Zagórska A., Czopek A., Jaromin A., Mielczarek-Puta M., Struga M., Stary D., Bajda M. Design, synthesis, and in vitro antiproliferative activity of hydantoin and purine derivatives with the 4-acetylphenylpiperazinylalkyl moiety. Materials, 2021, 14 (15), 4156.
Magli E., Kędzierska E., Kaczor A.A., Bielenica A., Severino B., Gibuła-Tarłowska E., Kotlińska J.H., Corvino A., Sparaco R., Esposito G., Albrizio S., Perissutti E., Frecentese F., Leśniak A., Bujalska-Zadrożny M., Struga M., Capasso R., Santagada V., Caliendo G., Fiorino F. Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands. Archiv der Pharmazie, 2021, 354 (5), 2000414.
Abram M., Rapacz A., Latacz G., Szulczyk B., Kalinowska-Tłuścik J., Otto-Ślusarczyk D., Struga M., Kamiński R.M., Kamiński K. Asymmetric synthesis and in vivo/in vitro characterization of new hybrid anticonvulsants derived from (2,5-dioxopyrrolidin-1-yl)phenylacetamides Bioorganic Chemistry, 2021, 109, 104751.
Szulczyk D., Bielenica A., Roszkowski P., Dobrowolski M.A., Olejarz W., Kmiecik S., Podsiad M., Struga M. Synthetic transition from thiourea-based compounds to tetrazole derivatives: Structure and biological evaluation of synthesized new n-(furan-2-ylmethyl)-1h-tetrazol-5-amine derivatives. Molecules, 2021, 26 (2), 323.
Szydłowski M., Garbicz F., Jabłonska E., Gorniak P., Komar D., Pyrzynska B., Bojarczuk K., Prochorec-Sobieszek M., Szumera-Cieckiewicz A., Rymkiewicz G., Cybulska M., Statkiewicz M., Gajewska M., Mikula M., Gołas A., Domagała J., Winiarska M., Graczyk-Jarzynka A., Białopiotrowicz E., Polak A., Barankiewicz J., Puła B., Pawlak M., Nowis D., Golab J., Tomirotti A.M., Brzozka K., Pacheco-Blanco M., Kupcova K., Green M.R., Havranek O., Chapuy B., Juszczynski P. Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies (2021) Cancer Research, 81 (23), 6029-6043.
Torun A., Hupalowska A., Trzonkowski P., Kierkus J., Pyrzynska B. Intestinal Microbiota in Common Chronic Inflammatory Disorders Affecting Children (2021) Frontiers in Immunology, 12, 642166.
Dlugolecka M., Szymanski J., Zareba L., Homoncik Z., Domagala-Kulawik J., Polubiec-Kownacka M., Czystowska-Kuzmicz M. Characterization of extracellular vesicles from bronchoalveolar lavage fluid and plasma of patients with lung lesions using fluorescence nanoparticle tracking analysis (2021) Cells, 10 (12), 3473.
Zareba L., Szymanski J., Homoncik Z., Czystowska-Kuzmicz M. Evs from balf—mediators of inflammation and potential biomarkers in lung diseases (2021) International Journal of Molecular Sciences, 22 (7), 3651.
Czystowska-Kuzmicz M., Whiteside T.L. The potential role of tumor-derived exosomes in diagnosis, prognosis, and response to therapy in cancer (2021) Expert Opinion on Biological Therapy, 21 (2), 241-258.
Siewiera J., Smoleński M., Jermakow N., Kot J., Brodaczewska K., Turyn J., Zabielska‐Kaczorowska M.A., Ludwig N., Szczepański M.J. Effect of hyperbaric oxygenation on blood cytokines and arginine derivatives; no evidence for induction of inflammation or endothelial injury (2021) Journal of Clinical Medicine, 10 (23), 5488.
Rubenich D.S., Omizzollo N., Szczepański M.J., Reichert T.E., Whiteside T.L., Ludwig N., Braganho, E. Small extracellular vesicle-mediated bidirectional crosstalk between neutrophils and tumor cells (2021) Cytokine and Growth Factor Reviews, 61, 16-26.
Głuszko A., Szczepański M.J., Whiteside T.L., Reichert T.E., Siewiera J., Ludwig N. Small extracellular vesicles from head and neck squamous cell carcinoma cells carry a proteomic signature for tumor hypoxia (2021) Cancers, 13 (16), 4176.
Mandapathil M., Szczepanski M.J., Jackson E.K., Lang S., Whiteside T.L. Breast cancer cell-derived adenosine enhances generation and suppressor function of human adaptive regulatory t cells (2021) Journal of Personalized Medicine, 11 (8), 754.
Piszczatowska K., Czerwaty K., Cyran A.M., Fiedler M., Ludwig N., Brzost J., Szczepański M.J. The emerging role of small extracellular vesicles in inflammatory airway diseases (2021) Diagnostics, 11 (2), 222.
Łacheta D., Poślednik K.B., Czerwaty K., Ludwig N., Molińska-Glura M., Kantor I., Jabłońska-Pawlak A., Miśkiewicz P., Głuszko A., Stopa Z., Brzost, J., Szczepański M.J. RAGE and HMGB1 Expression in Orbital Tissue Microenvironment in Graves' Ophthalmopathy. Mediators of Inflammation, 2021, 8891324.
Otto-Ślusarczyk D., Graboń W., Mielczarek-Puta M., Chrzanowska A. Teriflunomide – The common drug with underestimated oxygen - Dependent anticancer potential (2021) Biochemistry and Biophysics Reports, 28, 101141.
Strzyga-Łach P., Chrzanowska A., Podsadni K., Bielenica A. Investigation of the mechanisms of cytotoxic activity of 1,3-disubstituted thiourea derivatives (2021) Pharmaceuticals, 14 (11), 1097.
Chrzanowska A., Drzewiecka‐Antonik A., Dobrzyńska K., Stefańska J., Pietrzyk P., Struga M., Bielenica A. The cytotoxic effect of copper (Ii) complexes with halogenated 1,3‐disubstituted arylthioureas on cancer and bacterial cells (2021) International Journal of Molecular Sciences, 22 (21), 11415.
Chrzanowski J., Chrzanowska A., Graboń W. Glycyrrhizin: An old weapon against a novel coronavirus (2021) Phytotherapy Research, 35 (2), 629-636.
Otto-Ślusarczyk D., Mielczarek-Puta M., Graboń W. The real cytotoxic effect of artemisinins on colon cancer cells in a physiological cell culture setting. How composition of the culture medium biases experimental findings (2021) Pharmaceuticals, 14 (10), 976.
Mary Y.S., Mary Y.S., Bielenica A., Armaković S., Armaković S.J., Chandramohan V., Dammalli M. Investigation of the reactivity properties of a thiourea derivative with anticancer activity by DFT and
MD simulations (2021) Journal of Molecular Modeling, 27 (8), 217.
Skrzycki M. Superoxide dismutase and the sigma1 receptor as key elements of the antioxidant system in human gastrointestinal tract cancers (2021) Open Life Sciences, 16 (1), 1225-1239.
Kurpios-Piec D., Czeczot H., Podsiad M. Protective effect of quercetin and luteolin on LPS-induced oxidative stress in raw 264.7 cells (2021) Acta Poloniae Pharmaceutica - Drug Research, 78 (4), 527-538.
Ludwig N., Rubenich D.S., Zaręba Ł., Siewiera J., Pieper J., Braganhol E., Reichert T.E., Szczepański, M.J. Potential roles of tumor cell-and stroma cell-derived small extracellular vesicles in promoting a pro-angiogenic tumor microenvironment (2020) Cancers, 12 (12), 3599, 1-15.
Kulik K., Żyżyńska-Granica B., Kowalczyk A., Kurowski P., Gajewska M., Bujalska-Zadrożny M. Magnesium and morphine in the treatment of chronic neuropathic pain–a biomedical mechanism of action (2021) International Journal of Molecular Sciences, 22 (24), 13599.
Gumieniczek A., Berecka‐Rycerz A., Fornal E., Żyżyńska‐Granica B., Granica S. Comprehensive insight into chemical stability of important antidiabetic drug vildagliptin using chromatography (Lc‐uv and uhplc‐dad‐ms) and spectroscopy (mid‐ir and nir with pca) (2021) Molecules, 26 (18), 5632.
2020
Czystowska-Kuzmicz M, Whiteside TL. The potential role of tumor-derived exosomes in diagnosis, prognosis and response to therapy in cancer. Expert Opin Biol Ther. 2020 Aug 19. doi: 10.1080/14712598.2020.1813276. Online ahead of print.
Kubiak-Tomaszewska G, Tomaszewski P, Pachecka J, Struga M, Olejarz W, Mielczarek-Puta M, Nowicka G. Molecular mechanisms of ethanol biotransformation: enzymes of oxidative and nonoxidative metabolic pathways in human. Xenobiotica. 2020 Oct;50(10):1180-1201. doi: 10.1080/00498254.2020.1761571. Epub 2020 May 13.
Drzewiecka-Antonik A, Rejmak P, Klepka M, Wolska A, Chrzanowska A, Struga M. Structure and anticancer activity of Cu(II) complexes with (bromophenyl)thiourea moiety attached to the polycyclic imide. Journal of Inorganic Biochemistry. 111234. 10.1016/j.jinorgbio.2020.111234.
Jóźwiak M, Filipowska A, Fiorino F, Struga M. Anticancer activities of fatty acids and their heterocyclic derivatives. Eur J Pharmacol. 2020 Mar 15;871:172937. doi: 10.1016/j.ejphar.2020.172937. Epub 2020 Jan 17.
Olejarz W, Kubiak-Tomaszewska G, Chrzanowska A, Lorenc T. Exosomes in Angiogenesis and Anti-angiogenic Therapy in Cancers. International Journal of Molecular Sciences. 21. 10.3390/ijms21165840.
Żyżyńska-Granica B, Gierlikowska B, Parzonko A, Kiss AK, Granica S. The bioactivity of flavonoid glucuronides and free aglycones in the context of their absorption, II phase metabolism and deconjugation at the inflammation site. Food Chem Toxicol. 2020 Jan;135:110929. doi: 10.1016/j.fct.2019.110929. Epub 2019 Oct 31.
Żyżyńska-Granica B, Trzaskowski B, Dutkiewicz M, Zegrocka-Stendel O, Machcińska M, Bocian K, Kowalewska M, Koziak K. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor. Sci Rep. 2020 Feb 19;10(1):2886. doi: 10.1038/s41598-020-59798-3.
Hetmańczyk-Sawicka K, Iwanicka-Nowicka R, Fogtman A, Cieśla J, Włodarski P, Żyżyńska-Granica B, Filocamo M, Dardis A, Peruzzo P, Bednarska-Makaruk M, Koblowska M, Ługowska A. Changes in global gene expression indicate disordered autophagy, apoptosis and inflammatory processes and downregulation of cytoskeletal signalling and neuronal development in patients with Niemann-Pick C disease. Neurogenetics. 2020 Apr;21(2):105-119. doi: 10.1007/s10048-019-00600-6. Epub 2020 Jan 11.
Grodner B, Napiórkowska M. Capillary electrophoresis for the investigation of two novel aminoalkanol derivatives of 1,7-diethyl-8,9-diphenyl-4-azatricyclo[5.2.1.02,6] dec-8-ene-3,5,10-trione as potential anticancer drugs in water solution and serum. J Sep Sci. 2020 Feb;43(3):648-656. doi: 10.1002/jssc.201900648. Epub 2019 Nov 28.
Szulczyk D, Bielenica A, Roszkowski P, Dobrowolski MA, Olejarz W, Napiórkowska M, Struga M. Cytotoxicity Evaluation of Novel bis(2-aminoethyl)amine Derivatives. Molecules. 2020 Jun 18;25(12):2816. doi: 10.3390/molecules25122816.
Cabrera-Pardo JR, Fuentealba J, Gavilán J, Cajas D, Becerra J, Napiórkowska M. Exploring the Multi-Target Neuroprotective Chemical Space of Benzofuran Scaffolds: A New Strategy in Drug Development for Alzheimer's Disease. Front Pharmacol. 2020 Jan 31;10:1679. doi: 10.3389/fphar.2019.01679. eCollection 2019.
Olejarz W, Głuszko A, Cyran A, Bednarek-Rajewska K, Proczka R, Smith DF, Ishman SL, Migacz E, Kukwa W. TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome. Sleep Breath. 2020 Feb 20. doi: 10.1007/s11325-020-02029-w. Online ahead of print.
Szafarowski T, Sierdziński J, Ludwig N, Głuszko A, Filipowska A, Szczepański MJ. Assessment of cancer stem cell marker expression in primary head and neck squamous cell carcinoma shows prognostic value for aldehyde dehydrogenase (ALDH1A1). Eur J Pharmacol. 2020 Jan 15;867:172837. doi: 10.1016/j.ejphar.2019.172837. Epub 2019 Dec 5.
Szulczyk D., Bielenica A., Kedzierska E., Lesniak A., Pawlowska A., Bujalska-Zadrozny M., Saccone I., (...), Struga M. G protein-coupled receptor binding and pharmacological evaluation of indole-derived thiourea compounds. (2020) Archiv der Pharmazie, 353 (2).
Bielenica A., Beegum S., Mary Y.S., Mary Y.S., Thomas R., Armakovic S., Armakovic S.J., (...), Van Alsenoy C. Experimental and computational analysis of 1-(4-chloro-3-nitrophenyl)-3-(3,4-dichlorophenyl)thiourea. (2020) Journal of Molecular Structure, 1205.
Szulczyk D., Bielenica A., Roszkowski P., Dobrowolski M.A., Olejarz W., Napiorkowska M., Struga M. Cytotoxicity Evaluation of Novel bis(2-aminoethyl)amine Derivatives. (2020) Molecules, 25 (12).
Skrzycki M, Kaźmierczak B. The hidden role of the Sigma1 receptor in muscle cells. Journal of Receptors and Signal Transduction 2020 Jun;40(3):201-208.
Szulczyk D., Bielenica A., Głogowska A., Augustynowicz-Kopeć E., Dobrowolski M., Roszkowski P., Stępień K., Chrzanowska A., Struga M. Development of (4-methoxyphenyl)-1H-tetrazol-5-amine regioisomers as a new class of selective antitubercular agents. Eur J Med Chem. 2020; 186, 111882.
Chrzanowska A., Roszkowski P., Bielenica A., Olejarz W., Stępień K., Struga M. Anticancer and antimicrobal effects of novel ciprofloxacin fatty acids conjugates. Eur J Med Chem. 2020; 185, 111810.
2019
Gluszko A., Mirza S.M., Piszczatowska K., Kantor I., Struga M., Szczepanski M.J. The role of tumor-derived exosomes in tumor angiogenesis and tumor progression. Curr. Issues Pharm. Med. Sci. 2019; 32(4), 193–202.
Głuszko A.,Szczepański M.J., Ludwig N., M. Mirza S.M., Olejarz W. Exosomes in Cancer: Circulating Immune-Related Biomarkers. BioMed Research International. 2019 doi.org/10.1155/2019/1628029
Łacheta D., Miśkiewicz P., Głuszko A., Nowicka G., Struga M., Kantor I., Poślednik K.B., Mirza S., Szczepański M.J. Immunological Aspects of Graves' Ophthalmopathy. Biomed Res Int. 2019 doi: 10.1155/2019/7453260
Szulczyk D., Bielenica A., Kędzierska E., Leśniak A., Pawłowska A., Bujalska-Zadrożny M., Saccone I., Sparaco R., Fiorino F., Savchenko O., Struga M. G protein-coupled receptor binding and pharmacological evaluation of indole-derived thiourea compounds. Arch Pharm (Weinheim). 2019 doi: 10.1002
Grodner B., Napiórkowska M., Capillary electrophoresis for the investigation of two novel aminoalkanol derivatives of 1,7‐diethyl‐8,9‐diphenyl‐4‐azatricyclo[5.2.1.02,6] dec‐8‐ene‐3,5,10‐trione as potential anticancer drugs in water solution and serum, doi: 10.1002/jssc.201900648.
Ludwig N., Szczepanski M. J., Gluszko A., Szafarowski T., Azambuja J. H., Dolg L., Gellrich N-C., Kampmann A., Whiteside T. L., Zimmerer R. M. CD44(+) tumor cells promote early angiogenesis in head and neck squamous cell carcinoma. Cancer Letters. 2019; 467: 85-95.
Mielczarek-Puta M., Struga M., Roszkowski P. Synthesis and anticancer effects of conjugates of doxorubicin and unsaturated fatty acids (LNA and DHA). Med Chem Res. 2019; DOI: 10.1007/s00044-019-02443-0
Czopek A, Bucki A, Kołaczkowski M, Zagórska A, Drop M, Pawłowski M, Siwek A, Głuch-Lutwin M, Pękala E, Chrzanowska A, Struga M, Partyka A, Wesołowska A. Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability. Bioorg Med Chem. 2019 Sep 15;27(18):4163-4173.
Poślednik K. B., Miśkiewicz P., Jabłońska-Pawlak A., Kantor I., Szczepański M. J. Endoscopic decompression of orbit in Graves' orbitopathy. [Endoskopowa dekompresja oczodołu w orbitopatii tarczycowej]. Pol Merkur Lekarski. 2019 May 27;46(275):224-228.
Grosicka-Maciąg E., Kurpios-Piec D., Woźniak K., Kowalewski C., Szumiło M., Drela N., Kiernozek E., Suchocki P., Rahden-Staroń I. Selol (Se IV) modulates adhesive molecules in control and TNF-α-stimulated HMEC-1 cells. J Trace Elem Med Biol. 2019, 51:106-114.
Mielczarek-Puta M., Otto-Ślusarczyk D., Chrzanowska A., Filipek A., Graboń W. Telmisartan influences the antiproliferative activity of linoleic acid in human colon cancer cells. Nutr Cancer. 2019, 16:1-12.
Cichosz G., Czeczot H.,Minakowski D. Mleko – filar zdrowego odżywiania. Ewolucja wiedzy i oczekiwania. Kalendarz Stomatologiczny 2019. Med Tour Press International. Wydawnictwo Medyczne 2019, str. 351-357.
Czeczot H., Wolarek-Cheli Z. Suplementy witaminy K2 w Polsce. Bromat. Chem. Toksykol. 2019. LII, 1:1 – 9.
Drzewiecka-Antonik A. Wolska A., Cristovao B., Tarasiuk B., Barboza C.A., Osypiuk D., Starzyński J., Klepka M.T., Ferenc W., Grosicka-Maciąg E., Kurpios-Piec D., Struga M. Structural characterization and cytotoxic evaluation of Cu(II), Co(II) and Ni(II) complexes with herbicide 4-chloro-2-methylphenoxyacetic acid. Polyhedron. 2019, 165:86-96.
Napiórkowska M., Cieślak M., Kaźmierczak-Barańska J., Królewska-Golińska K., Nawrot B. Synthesis of new derivatives of benzofuran as potential anticancer agents. Molecules. 2019, 24:1529.
Cieślak M., Kaźmierczak-Barańska J., Królewska-Golińska K., Napiórkowska M., Stukan I., Wojda U., Nawrot B., New Thalidomide-Resembling Dicarboximides Target ABC50 Protein and Show Antileukemic and Immunomodulatory Activities, Biomolecules. 2019 Sep; 9(9): 446.
Królewska-Golińska K., Cieślak M.J., Sobczak M., Dolot R., Radzikowska-Cieciura E., Napiórkowska M., Wybrańska I., Nawrot B. Novel benzo[b]furans with anti-microtubule activity upregulate expression of apoptotic genes and arrest leukemia cells in G2/M phase. Anticancer Agents Med Chem. 2019, 19: 375-388
Jóźwiak M., Struga M., Roszkowski P., Filipek A., Nowicka G., Olejarz W. Anticancer effects of alloxanthoxyletin and fatty acids esters – In vitro study on cancer HTB-140 and A549 cells. Biomedicine & Pharmacotherapy. 2019, 110:618-630.
Olejarz W., Wrzosek M., Jóźwiak M., Grosicka-Maciąg E., Roszkowski P., Filipek A., Cychol A., Nowicka G., Struga M. Synthesis and anticancer effects of α-lipoic ester of alloxanthoxyletin. Med. Chem. Res. 2019, 5: 788-796.
Struga M., Szulczyk D., Stefańska J., Patent WO2019045581A1
2018
Graboń W., Otto-Ślusarczyk D., Barańczyk-Kuźma A. Influence of oxygen on the Warburg effect: do cancer cells produce lactate only from glucose? Postepy Hig Med Dosw. 2018, 72: 481-490.
Cichosz G., Czeczot H., Bielecka M.M. Znaczenie składników odżywczych z produktów mleczarskich w profilaktyce otyłości u dzieci i młodzieży/The importance of nutrie nt components of dairy products in the production of obesity in children and adolescents. Bromatologia i Chemia Toksykologiczna. 2018, 1:58-66.
Bielenica A., Sanna G., Madeddu S., Giliberti G., Stefańska J., Kozioł A.E., Savchenko O., Strzyga-Łach P., Chrzanowska A., Kubiak-Tomaszewska G., Struga M. Disubstituted 4-chloro-3-nitrophenylthiourea derivatives: antimicrobial and cytotoxic studies. Molecules. 2018, 23:2428.
Bielenica A., Drzewiecka-Antonik A., Rejmak P., Stefańska J., Koliński M., Kmiecik S., Lesyng B., Włodarczyk M., Pietrzyk P., Struga M. Synthesis, structural and antimicrobial studies of type II topoisomerase-targeted copper(II) complexes of 1,3-disubstituted thiourea ligands. J Inorg Biochem. 2018, 182:61-70.
Napiórkowska M., Madeddu S., Giliberti G., Sanna G. Cytotoxic properties of selected derivatives of benzofurans - preliminary studies. Acta Poloniae Pharmaceutica - Drug Research. 2018, 75:255-263.
Jóźwiak M., Struga M., Roszkowski P., Filipek A., Nowicka G., Olejarz W. Anticancer effects of alloxanthoxyletin and fatty acids esters - In vitro study on cancer HTB-140 and A549 cells. Biomed Pharmacother. 2019, 110:618-630.
Sanna G., Madeddu S., Giliberti G., Piras S., Struga M., Wrzosek M., Kubiak-Tomaszewska G., Koziol A.E., Savchenko O., Lis T., Stefanska J., Tomaszewski P., Skrzycki M., Szulczyk D. Synthesis and biological evaluation of novel indole-derived thioureas. Molecules. 2018, 23:1-17.
Olejarz W., Łacheta D., Głuszko A., Migacz E., Kukwa W., Szczepański M.J., Tomaszewski P., Nowicka G. RAGE and TLRs as key targets for antiatherosclerotic therapy. Biomed Res Int. 2018, 2018:7675286.
Jóźwiak M., Stępień K., Wrzosek M., Olejarz W., Kubiak-Tomaszewska G., Filipowska A., Filipowski W., Struga M. Synthesis, structural studies and biological evaluation of connections of thiosemicarbazide, 1,2,4-triazole and 1,3,4-thiadiazole with palmitic acid. Molecules. 2018, 23:1-20.
Szulczyk D., Dobrowolski M.A., Roszkowski P., Bielenica A., Stefańska J., Koliński M., Kmiecik S., Jóźwiak M., Wrzosek M., Olejarz W., Struga M. Design and synthesis of novel 1H-tetrazol-5-amine based potent antimicrobial agents: DNA topoisomerase IV and gyrase affinity evaluation supported by molecular docking studies. Eur J Med Chem. 2018, 156:631-640.
Klepka M.T., Drzewiecka-Antonik A., Wolska A., Rejmak P., Struga M. Structural studies of Cu(II) complexes with coumarin acid derivatives obtained using direct and electrochemical synthesis. Chem. Phys. Lett. 2018, 691:190-195.
2017 i wcześniejsze
Bielenica A., Stepien K., Sawczenko A., Lis T., Koziol A.E., Madeddu S., Collu D., Iuliano F., Kosmider A., Struga M. Synthesis, structural studies and biological evaluation of halogen derivatives of 1,3-disubstituted thiourea. Lett Drug Des Discov. 2017, 14: 636-646.
Bielenica A., Szulczyk D., Olejarz W., Madeddu S., Giliberti G., Materek I.B., Koziol A.E., Struga M. 1H-Tetrazol-5-amine and 1,3-thiazolidin-4-one derivatives containing 3-(trifluoromethyl)phenyl scaffold: Synthesis, cytotoxic and anti-HIV studies. Biomed Pharmacother. 2017, 94:804-812.
Aswathy V.V., Mary Y., Jojo P.J., Panicker C.Y., Bielenica A., Armakovic S., Armaković S.J., Brzózka P., Krukowski S., Van Alsenoy C. Investigation of spectroscopic, reactive, transport and docking properties of 1-(3,4-dichlorophenyl)-3-[3-(trifluoromethyl)phenyl]thiourea (ANF-6): Combined experimental and computational study. J. Mol. Structure. 2017, 1134:668-680.
Menon V.V., Mary Y.S, Mary Y.S., Panicker C.Y., Bielenica A., Armakovic S., Armaković S. J., Van Alsenoy C. Combined spectroscopic, DFT, TD-DFT and MD study of newly synthesized thiourea derivative. J. Mol. Structure. 2017, 1155:184-195.
Bielenica A., Sanna G., Madeddu S., Struga M., Jóźwiak M., Kozioł A.E., Sawczenko A., Materek I.B., Serra A., Giliberti G. New thiourea and 1,3-thiazolidin-4-one derivatives effective on the HIV-1 virus. Chem Biol Drug Des. 2017, 90(5):883-891.
Ostrowska K., Olejarz W., Wrzosek M., Głuszko A., Nowicka G., Szczepański M., Materek IB., Kozioł AE., Struga M. Anticancer effects of O-aminoalkyl derivatives of alloxanthoxyletin and seselin. Biomed Pharmacother., 2017, 95:1412-1424.
Kalinowska D., Klepka M.T., Wolska A., Drzewiecka-Antonik A., Ostrowska K., Struga M. Structural study of Cu(II) complexes with benzo[b]furancarboxylic acids. Nuclear Inst. and Methods in Physics Research, B. 2107, 411:116-120.
Usarek E, Barańczyk-Kuźma A, Kaźmierczak B, Gajewska B, Kuźma-Kozakiewicz M. Validation of qPCR reference genes in lymphocytes from patients with amyotrophic lateral sclerosis. PLoS One. 2017, 22;12(3):e0174317.
Dobrowolski M.A., Roszkowski P., Struga M., Szulczyk D., The unexpected product of Diels-Alder reaction between “indanocyclon” and maleimide. J. Mol. Structure, 2017, 1130: 573-578.
Szulczyk D, Tomaszewski P, Jóźwiak M, Kozioł AE, Lis T, Collu D, Iuliano F, Struga M. Synthesis and biological activities of ethyl 2-(2-pyridylacetate) derivatives containing thiourea, 1,2,4-triazole, thiadiazole and oxadiazole moieties. Molecules. 2017 Mar 6;22(3), 409.
Drzewiecka-Antonik A, Rejmak P, Klepka MT, Wolska A, Pietrzyk P, Stępień K, Sanna G, Struga M. Synthesis, structural studies and biological activity of novel Cu(II) complexes with thiourea derivatives of 4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione. J Inorg Biochem. 2017, 176:8-16.
Dybała I., Wawrzycka-Gorczyca I., Struga M. Structural and computational study of 1,2,4-triazolin-5-thione derivative and its DMSO solvate. J. Mol. Structure, 2017, 1147:786-796.
Skrzycki M., Czeczot H., Mielczarek-Puta M., Otto-Slusarczyk D., Grabon W., Effect of different concentrations of oxygen on expression of sigma 1 receptor and superoxide dismutases in human colon adenocarcinoma cell lines, J. Recept. Sig. Transd., 2017, 37(3):252-258.
Stefańska J, Stępień K, Bielenica A, Wrzosek M, Struga M. Antistaphylococcal activity of selected thiourea derivatives. Pol J Microbiol. 2017 Jan 2;65(4):451-460.
Grodner B., Napiórkowska M.. Characterization and inhibition studies of tissue nonspecific alkaline phosphatase by aminoalkanol derivatives of 1,7-dimethyl-8,9-diphenyl-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5,10-trione, new competitive and non-competitive inhibitors, by capillary electrophoresis. J Pharm Biomed Anal. 2017, 143:285-290.
Graboń W., Otto-Ślusarczyk D., Chrzanowska A., Mielczarek-Puta M., Joniec-Maciejak I., Słabi K., Barańczyk-Kuźma A. Lactate Formation in Primary and Metastatic Colon Cancer Cells at Hypoxia and Normoxia, Cell Biol.Funct., 2016, 34(7), 483-490
Kuran B., Napiórkowska M., Kossakowski J.,Cielak M., Kaźmierczak-Barańska J., Królewska K., Nawrot B. New, substituted derivatives of dicarboximides and their cytotoxic properties, Anti-Cancer Agents Med. Chem., 2016, 16, 852-864
Usarek E., Graboń W., Kaźmierczak B., Barańczyk-Kuźma A., Targeting the expression of glutathione- and sulfate-dependent detoxification enzymem in HepG2 cells by oxygen in minima and amino acid enriched medium, Exp. Mol. Pathol.,2016, 100, 82-86
Czeczot H., Fitoestrogeny – związki o cennych właściwościach biologicznych i farmakologicznych, Biochem. Farm., 2016, 72, 110 - 117
Czeczot H., Potencjał neuroprotekcyjny flawonoidów, Biochem.Farm., 2016, 72(11) 745-750
Czeczot H., Cynk –pierwiastek niezbędny dla zdrowia, Biochem. Farm., 2016, 72, 359 -365
Sheena Mary Y., Aswathy V.V.,Panicker C.Y., Bielenica A., Brzoska P., Savczenko O., Armakovic S., Armakovic S.J.,van Alsenoy Ch., Spectroscopic, single crystal XRD structure, DFT and molecular dynamics investigation of 1-(3-chloro-4-fluorophenyl)-3-[3-(trifluoromethyl)phenyl] thiourea, RSC Adv., 2016, 6, 111997-112015
Cichosz G.,Czeczot H., Bielecka M.M., Odtłuszczone produkty mleczarskie –dietetyczne nieporozumienie, Bromat. Chem.Toxicol., 2016, XLIX, 160 -167
Pakosińska – Parys M., Zimniak A., Chodkowska A., Jagiełło-Wójtowicz E., Głowala M., Struga M., Synthesis, structure and pharmacological evaluation of 1-(1H-pyrrol-1-ylmethyl)-4-azatricyclo[5.2.1.02,6] dec-8-ene-3,5-dione, Acta Pol. Pharm. –Drug Res., 2016, 73, 931 -936
Fiorino F., Ciano A., Magli E., Severino B., Corvino A., Perissutti E., Frecentese F., Di Vaio P., Izzo A.A., Capasso R., Massarelli P., Nencini C., Rossi I., Kedzierska E., Orzelska-Gorka J., Bielenica A., Santagada V., Caliendo G., Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus, Eur. J. Med. Chem., 2016, 110, 133-150
Bielenica A., Kedzierska E., Kolinski M., Kmiecik S., Kolinski A., Fiorino F., Severino B., Magli E., Corvino A., Rossi I., Massarelli P., Kozioł A.E.,Sawczenko A., Struga M. 5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives, Eur. J. Med. Chem., 2016, 116, 173-186
Bielenica A., Stefańska J., Kozioł A.E.,Iuliano F., Collu D., Sanna G., Jozwiak M., Struga M. Thiourea derivatives of 4-azatricyclo[5.2.2.02,6] undec -8-ene-3,5-dione – synthesis and biological activity, Acta Pol. Pharm. – Drug Res., 2016, 73(3), 693-703
Bielenica A., Stepien K., Napiorkowska A., Augustynowicz –Kopec E., Krukowski S., Wlodarczyk M., Struga M. Synthesis an antimicrobial activity of 4-chloro-3-nitrophenylthiourea derivatives targeting bacterial type II topoisomerases, Chem. Biol. Drug Des., 2016, 87,905-917
Stefanska J, Stepien K, Bielenica A, Szulczyk D, Miroslaw B, Koziol AE, Sanna G, Iuliano F, Madeddu S, Jozwiak M, Struga M. Antimicrobial and anti-biofilm activity of thiourea derivatives bearing 3-amino-1H-1,2,4-triazole scaffold. Med Chem. 2016;12(5):478-88.
Strzyga-Łach P., Czeczot H. Rola flawonoidów w modulacji stanu zapalnego, Pol. Merkur. Lek., 2016, 40(236), 134-140
Otto-Ślusarczyk D., Graboń W., Mielczarek-Puta M. Aminotransferaza asparaginianowa – kluczowy enzym w metabolizmie ogólnoustrojowym człowieka, Postępy Hig. Med. Dosw., 2016, 70, 219-230
Kuźma-Kozakiewicz M., Kaźmierczak B., Chudy A., Gajewska B.,Barańczyk-Kuźma A. Alteration of motor protein expression involved in bidirectional transport in peripheral blood mononuclear cells of patients with amyotrophic lateral sclerosis, Neurodegener.Dis., 2016, 16(3-4), 235-244
Grodner B., Łukaszkiewicz J., Napiórkowska M. Determination of the stereoisomers in aqueous medium and serum and validation studies of racemic aminoalkanol derivatives of 1,7-dimethyl-8,9-diphenyl-4-azatricyclo[5.2.1.0(2,6) ]dec-8-ene-3,5,10-trione, potential new anticancer drugs, by capillary electrophoresis. J Sep Sci. 2016 39:3246-53.
Stefanska J, Nowicka G, Struga M, Szulczyk D, Koziol AE, Augustynowicz-Kopec E, Napiorkowska A, Bielenica A, Filipowski W, Filipowska A, Drzewiecka A, Giliberti G, Madeddu S, Boi S, La Colla P, Sanna G. Antimicrobial and anti-biofilm activity of thiourea derivatives incorporating a 2-aminothiazole scaffold. Chem Pharm Bull (Tokyo). 2015;63(3):225-36.
Cichosz G., Czeczot H., Ambroziak A., Bielecka M.M. Wpływ przechowywania na profil kwasów tłuszczowych w mlekozastępczych preparatach do żywienia niemowląt, Bromat. Chem. Toksykol., 2015, 48(4), 605-614
Domitrz I.,Koter M., Chołojczyk M., Domitrz W., Barańczyk-Kuźma A., Kamińska A. Changes in serum amino acidsin migraine patients without and with aura and their possible usefulness in the study of migraine patogenesis, CNS& Neurol. Dis. – Drug Targets, 2015, 14(3), 345-349
Skrzycki M., Czeczot H., Chrzanowska A., Otto-Ślusarczyk D. Poziom ekspresji izoenzymów dysmutazy ponadtlenkowej w pierwotnych i przerzutowych komórkach raka jelita grubego w hipoksji i normoksji, Pol. Merkur. Lek., 2015, 39(233), 281-286
Czeczot H., Strzyga P., Skrzycki M. Miedź w zdrowiu i chorobie, Farm. Pol., 2015, 71(9), 586- 592
Cichosz G., Czeczot H., Bielecka M.M., Odtłuszczone produkty mleczarskie-dietetyczne nieporozumienie, Bromat. Chem. Toksykol., 2015, 48(4), 605-614
Strzyga P., Czeczot H. Nowe spojrzenie na ceruloplazminę, Farm. Pol., 2015, 71(10), 609- 614
Gajewska B., Kaźmierczak B., Kuźma-Kozakiewicz M., Jamrozik Z., Barańczyk-Kuźma A. GSTP1 polymorphisms and their association with glutathione transferase and peroxidase activity in patients with motor neuron disease,CNS& Neurol. Dis. – Drug Targets, 2015, 14(10), 1328-1333
Bielenica A., Stefańska J., Stępień K., Napiórkowska A., Augustynowicz-Kopeć E., Sanna G., Madeddu S., Boi S.,Giliberti G., Wrzosek M.,Struga M. Synthesis, cytotoxicity and antymicrobial activity of thiourea derivatives incorporating 3-(trifluoromethyl)phenyl moiety, Eur.J.Med.Chem., 2015, 101, 111-125
Stefańska J., Nowicka G., Struga M., Szulczyk D., Kozioł A.E., Augustynowicz-Kopeć E., Napiórkowska A., Bielenica A., Filipowski W., Filipowska A.,Drzewiecka A., Giliberti G., Madeddu S.,Boi S., La Colla P., Sanna G. Antimicrobial and anti-biofilm activity of thiourea derivatives incorporating a 1-aminothiazole scaffold, Chem. Pharm. Bull., 2015, 63(3), 225-236
Bielenica A., Kedzierska E., Fidecka S., Maluszyńska H., Mirosław B., Kozioł A.E., Stefańska J., Madeddu S., Giliberti G., Sanna G.,Struga M. Synthesis, Antimicrobial and Pharmaceutical Evaluation of Thioureaderivatives of 4H-1,2,4-triazole, Lett. Drug Des. Disco., 2015, 12(4), 263-276
Cichosz G., Czeczot H. Tłuszcz mlekowy-unikalny pod każdym względem, Pol. Merkur. Lek., 2015, 38, (225), 174-179
Krawiecka M., Kuran B., Kossakowski J.,Cielak M., Kaźmierczak-Barańska J., Królewska K., Nawrot B. Synthesis and cytotoxic properties of halogen and aryl-/heteroarylpiperazinyl derivatives of benzofurans, Anti-Cancer Agents in Med. Chem., 2015, 15, 115-121
Napiórkowska M., Cieślak M., Kaźmierczak-Barańska J., Królewska K., Czapla A., Kuran B. Synthesis and preliminary studies of biological activity of amino derivatives of 4-azatricyclo-[5.2.1.0]dec-8-ene-3,5-dione with silicon in the structure, Heterocyc.Commun., 2015, 21(1), 19-24
Remis K.S., Mary Y. S, Varghese H.T., Panicker C.Y., Pakosińska-Parys M., van Alsenoy C. Spectral investigations, DFT computations and molecular docking studies of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-{3-[4-(2-methylphenyl)piperazin-1-yl]propyl}- 4-azatricyclo [5.2.1.0] dec-8-ene-3,5-dione, J. Mol. Struct., 2015, 1098, 130-145
Czeczot H., Cichosz G., Ambroziak A. Poziom peroksydacji lipidów w mlekozastępczych preparatach do żywienia początkowego niemowląt, Pol. Merkur. Lek., 2015, 224, 93-99
Cichosz G., Czeczot H., Ambroziak A., Treszczyńska B. Evaluation of lipid oxidative stability in infant formulas, Int.Rev.Allergol.Clin. Immunol. Family Med., 2015, 21(1), 32-37
Zajda M., Kaźmierczak B., Zakrzewska-Pniewska B. Aquaporin-4: A novel diagnostic biomarker for seronegative neuromyelitis optica, Multiple Sclerosis Journal, 2015, 22(1) 125-126
Kurpios-Piec D., Woźniak K., Kowalewski C., Gajewska B., Rahden-Staroń I. Thiram modulates pro-inflammatory mediators in RAW 264.7 murine macrophage cells, Immunopharmacol. Immunotoxicol., 2015, 37(1), 90-102
Kurpios-Piec D., Grosicka-Maciąg E., Woźniak K., Kowalewski C., Kiernozek E., Szumiło M., Rahden-Staroń I. Thiram activates NF-kappaB and enhances ICAM-1 expression in human microvascular endothelial HMEC-1 cells, Pestic. Biochem. Physiol., 2015, 118, 82-89
Kraj L., Krawiec M., Koter M., Graboń W., Kraj G., Chołojczyk M., Kulus M., Barańczyk-Kuźma A. Altered L-arginine metabolizm in children with controlled astma, Allergy and Asthma Proceedings, 2014, 35(5), 80-83
Kraj L., Krawczyk J. Oxycodone/nalaxone as a therapeutic option in a patient with chronic pain and opioid-induced bowel dysfunction. Contemp. Oncol., 2014, 18(3), 215-217
Krawczyk J., Kraj L., Jędrzejczak W. Metabolic and nutritional aspects of cancer. Postępy Higieny I Medycyny Doswiadczalnej, 2014, 68, 1008-1014
Chrzanowska A., Graboń W., Mielczarek-Puta M., Barańczyk-Kuźma A. Significance of arginase determination in body fluids patients with hepatocellular carcinoma and liver cirrosis before and after surgical treatment. Clin. Biochem., 2014, 47, 1056-1059
Cichosz G., Czeczot H. Tłuszcz mlekowy w profilaktyce chorób dietozależnych, Bromat. Chem. Toksykol., 2014, 47(1), 1-9
Cichosz G., Czeczot H. Mleko-produkt o wyjątkowym potencjale immunostymulacyjnym, Pediatr. Pol., 2014, 89, 54-59
Cichosz G., Czeczot H. Calcium-essential for everybody, Pol. Merkur. Lek., 2014, 36(216), 407-411
Skrzycki M., Czeczot H. Multiple protective functions of Sigma 1 receptor, Current protein& Peptide Science, 2014, 15(8), 796-811
Renjith R., Sheena Mary Y., Yohannan Panicker C., Varghese H.T., Pakosińska-Parys M.,van Alsenoy C., Manojkumar T.K. Spectroscopic (FT-IR, FT-Raman), first order hyperpolarizability, NBO analysis, HOMO and LUMO analysis of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-{3-[4-3-methoxyphenyl]piperazin-1-yl}-4-azatricyclo[5.2.1.0]dec-8-ene-3,5-dione by density functional methods, Spectrochimica Acta. Part A-Molecular and Biomolecular Spectroscopy, 2014, 124, 500- 513
Renjith R., Sheena Mary Y., Yohannan Panicker C., Varghese H.T., Pakosińska-Parys M.,van Alsenoy C., Manojkumar T.K. Vibrational spectroscopic and computational study of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-{3-[4-3-methoxyphenyl] piperazin-1-yl}-4-azatricyclo[5.2.1.0]dec-8-ene-3,5-dione, Spectrochimica Acta. Part A-Molecular and Biomolecular Spectroscopy, 2014,124, 480- 491
Renjith R., Sheena Mary Y., Yohannan Panicker C., Varghese H.T., Pakosińska-Parys M.,van Alsenoy C., Al-Saadi A.A.Spectroscopic (FT-IR, FT-Raman)investigations and quantum chemical calculations of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-{3-[4-3-methoxyphenyl]piperazin-1-yl}-4-azatricyclo[5.2.1.0]dec-8-ene-3,5-dione, Spectrochimica Acta. Part A-Molecular and Biomolecular Spectroscopy, 2014,129, 438- 450
Krawiecka M., Kuran B., Kossakowski J., Cieślak M., Kaźmierczak-Barańska J.,Królewska K., Nawrot B. Synthesis and cytotoxic properties of halogen and aryl-/heteroarylpiperazinyl derivatives of benzofurans, Anticancer Agents Med. Chem., 2014, 15(1), 115-121
Grodner B., Łukaszkiewicz J., Kuran B., Krawiecka M. Capillary electrophoresis separation of aminoalkanol derivatives of 1,7-dimethyl-diphenyl-4-azatricyclo[5.2.1.0]dec-8-ene-3,5,10-trione as potential anticancer drugs, J. Sep. Sci., 2014, 37, 3564-3570
Mirosław B., Kozioł A.E., Bielenica A., Dziuba K., Struga M. Substituent effect on supramolecular motifs in series of succinimide polycyclic keto derivatives –spectroscopic, theoretical and crystallographic studies. J. Mol. Struct., 2014, 1074, 695-702
Haggmark A., Mikus M., Mohsenchian A., Hong M-G., Forsstrom B., Gajewska B., Barańczyk-Kuźma A., Nilsson P. Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosis, Ann. Clin. Transl. Neurol., 2014, 1(8), 544-553
Chełstowska B., Kuźma-Kozakiewicz M. Is cerebrospinal fluid obtained for diagnostic purpose a good material for biomarker studies in amyotrophic lateral sclerosis, Biomarkers, 2014, 19(7), 571-577
Cichosz G., Czeczot H. Kontrowersje wokół białek diety, Pol. Merkur. Lek., 2013, 35(210), 398-401
Kuźma-Kozakiewicz M.,Berdyński M., Merita M., Takahashi Y., Kawata A., Ken-Ichi K., Kaźmierczak B., Łusakowska A.,GotoJ.,Tsuji S., Żekanowski C.,Kwieciński H. Recurrent K3E mutation in Cu/Zn superoxide dismutase gene associated with amyotrophic lateral sclerosis, Amyotroph. lateral scler. frontotemporal degener., 2013, 14(7-8), 608-614
Kuran B., Kossakowski J., Cieslak M., Kierzkowska M., Kaźmierczak-Barańska J., Królewska K., Cyrański M.K., Stępień D.K., Krawiecka M. Synthesis and biological activity of novel series of heterocyclic compounds containing succinimide moiety, Heterocyc. Commun., 2013, 19(4), 287-296
Krawiecka M., Kuran B., Kossakowski J., Kierzkowska M., Młynarczyk G., Kaźmierczak-Barańska J., Królewska K., Cieślak M. Synthesis and biological activity of 6-substituted-5-acetyl-4,7-dimethoxybenzofuran derivatives, Heterocyc. Commun., 2013, 19(4), 281-286
Bielenica A., Kozioł A.E.,Struga M.Binding models of chain arylpiperazines to 5HT1a, 5HT2a and 5-HT7 receptors, Mini-reviews in Medicinal Chemistry, 2013, 13(10), 1516-1539
Bielenica A., Kozioł A.E., Struga M.Computational methods in determination of pharmacophore models of 50HT1A,5A and 5-HT7 receptors, Mini-reviews in Medicinal Chemistry, 2013, 13(7), 933-951
Pakosińska-Parys M., Kossakowski J., Mirosław B., Kozioł A.E., Stefańska J. Synthesis and pharmacological activity of 1,8,11,11 –tetramethyl-4-azatricyclo[5.2.2.02.6] undec-8-ene-3,5-dione derivatives, Acta Pol. Pharm.-Drug Res., 2013, 70(3), 505-515
Kuran B., Krawiecka M., Kossakowski J., Koronkiewicz M., Chilmończyk Z. Proapoptotic activity of heterocyclic compounds containing succinimide moiety in the promyelocytic leukemia cell line HL-60. Acta Pol. Pharm.-Drug Res., 2013, 70(3), 459-468
Szulczyk D., Bielenica A., Dobrowolski M.A., Dobrzycki Ł., Krawiecka M., Kuran B., Struga M. Synthesis and structure evaluation of new complexbutylarylpiperazin-1-yl derivatives, Med. Chem. Res., 2013, 1(2), 1-16
Krawiecka M., Kuran B., Kossakowski J., Kierzkowska M., Młynarczyk G., Cieślak M., Kaźmierczak-Barańska J., Królewska K., Dobrowolski M.A. Synthesis and biological activity of novel series of 1,3-benzooxazol-2(3H)-one derivatives, Acta Pol. Pharm.-Drug Res., 2013, 70(2), 245-253
Bielenica A., Struga M., Mirosław B., Kozioł Anna E., Kossakowski J., Sanna G., La colla P., Giliberti G. Synthesis and biological evaluation of N-substituted polycyclic imides derivatives, Acta Pol. Pharm.-Drug Res., 2013, 70(5), 809-822
Skrzycki M., Czeczot H., Altered expression level of Sigma1 receptor gene in human colorectal cancer. J. Recept. Sign. Transd., 2013, 33(5), 313-318
Kozakiewicz M., Maruszak A., Kwieciński H., Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration, Annals of Clinical and Laboratory Science, 2013, 43(2), 151-153
Jamrozik Z, Berdynski M, Zekanowski C, Baranczyk-Kuzma A, Sławek J, Kuzma-Kozakiewicz M, Maruszak A, Kwiecinski H. Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration. Ann Clin Lab Sci. 2013 Spring;43(2):151-3.
Cichosz G., Czeczot H. Żywieniowy fenomen mleka, Olsztyn-Warszawa, 2013
Czeczot H., Skrzycki M., Majewska- Wierzbicka M. Podsiad M., Salamatin R., Grytner-Zięcina B. The antioxidant defence mechanisms of parsie and host after chronic Hymenolepsis diminuta infestation of the rat, Pol. J. Vet. Sci., 2013, 16 (1), 121-123
Grosicka-Maciąg E., Szumiło M., Czeczot H., Kurpios-Piec D., Skrzycki M., Rahden-Staroń I. Modulation of antioxidant defense systems by the dithiocarbamate fungicides maneb and zineb in Chinese hamster V79 cells and the role of N-acetyl-L-cysteine, Food and Chem. Toxicol., 2013, 60, 130-134
Kuźma-Kozakiewicz M., Chudy A., Kaźmierczak B., Dziewulska D., Usarek E., Barańczyk-Kuźma A., Dynactin deficiency in the CNS of humans with sporadic ALS and mice with genetically determined motor neuron degeneration, Neurochem. Res., 2013, 38, 2463-2473
Kuźma-Kozakiewicz M., Kaźmierczak B., Usarek E., Barańczyk-Kuźma A., Changes in kinesin expression in the CNS of mice with dynein heavy chain 1 mutation, Acta Biochim Pol., 2013, 60(1), 51-55
Kuźma-Kozakiewicz M., Barańczyk-Kuźma A., Chudy A., Gajewska B., Dziewulska D., Usarek E., Barańczyk-Kuźma A., Kinesin expression in the central nervous system of humans and transgenic hSOD1G93A mice with amyotrophic lateral sclerosis, Neurodegener. Dis., 2013, 12, 71-80
Gaweł M., Jamrozik Z., Szmidt-Sałkowska E., Slawek J., Gawel D. Electrophysiological features of lower motor neuron involvement in progressive supranuclear palsy, J. Neurol. Sci., 2013, 324, 136-139
Majewska-Wierzbicka M., Czeczot H. Przeciwnowotworowe działanie flawonoidów, Pol. Merkur. Lek., 2012, XXXIII, 198, 364-370
Majewska-Wierzbicka M., Czeczot H. Flawonoidy w prewencji i leczeniu chorób układu sercowo-naczyniowego, Pol. Merk. Lek., 2012, XXXII, 187, 51-55
Cichosz G., Czeczot H. Kontrowersje wokół cholesterolu pokarmowego. Pol. Merkur. Lek., 2012, 33, 193, 38-42
Cichosz G., Czeczot H. Tłuszcz mlekowy w profilaktyce chorób nowotworowych, Pol. Merk. Lek., 2012, 33, 195, 168-172
Czeczot H., Skrzycki M., Rola stanu zapalnego w patogenezie raka jelita grubego, Kształcenie Podyplomowe, 2012, V (2),20-29
Czeczot H., Majewska M., Flawonoidy w prewencji i leczeniu chorób układu sercowo-naczyniowego, Pol. Merkur. Lek., 2012, XXXII (187), 51-55
Mielczarek-Puta M., Graboń W., Barańczyk-Kuźma A. Metabolizm L-argininy w komórkach raka jelita grubego, Kształcenie podyplomowe, 2012, V(2), 30-35
Czeczot H., Skrzycki M., Majewska M., Podsiad M., Salamatin, Twardowska-Małczyńska J., Grytner-Zięcina B. Changes of enzymatic antioxidant system in the small intestine of rats after the chronic invasion by Hymenolepsis diminuta (Cestoda, Hymenolepididae), Helminthologia, 2012, 49(4), 233-240
Rahden-Staroń I, Grosicka-Maciąg E, Kurpios-Piec D., Czeczot H, Grzela T, Szumiło M. The effects of sodium diethyldithiocarbamate in Chinese hamster fibroblasts V79 cell in relation to cytotoxicity, oxidative stress, glutathione and apoptosis. Arch. Toxicol., 2012, 86: 1841-1850
Janowska B., Kurpios-Piec D., Prorok P., Szparecki G., Komisarski M., Kowalczyk P., Janion C., Tudek B. (2011) Role of damage-specific DNA polimerases in M13 phage mutagenesis induced by a major lipid peroxidation product trans-4-hydroksy-2-nonenal, Mutat.Res.: Fundam. Mol. Mech. Mutagen., 2012, 729 (1-2), 44-51
Grosicka-Maciąg E., Kurpios-Piec D., Szumiło M., Grzela T., Rahden-Staroń I. (2012) Dithiocarbamate fungicide zineb induces oxidative stress and apoptosis in Chinese hamster lung fibroblasts, Pestic.Biochem. Physiol., 2012, 102, 95-101
Czeczot H., Skrzycki M., Majewska M. Podsiad M., Salamatin R.,Twarowska-Małczyńska J., Grytner-Zięcina B. Hymenolepsis diminuta:Experimental studies on the antioxidant system with short and long term infection periods in the rats, Exp. Parasitol., 2011, 129,158-163
Krawczyk J., Korta T., Kraj L. Choroba nowotworowa a metabolizm, Post. Zyw. Klin., 2011, 6(3), 31-35
Gaweł D. Seed P.C. (2011) Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence, Virulence, 2011, 2 (3), 222-232
Gaweł D., Jonczyk P., Fijałkowska I.J., Schaaper R.M. (2011) dnaX36 Mutator of Escherichia coli: Effects of the τ subunit of the DNA polymerase III holoenzyme on chromosomal DNA replication fidelity, J. Bacteriol.,193 (1), 296-300
Kaźmierczak B., Kuźma-Kozakiewicz M., Usarek E., Barańczyk-Kuźma A., (2011) Differences in glutathione S-transferase pi expression in transgenic mice with symptom sof neurodegeneration, Acta Biochim. Polon., 58, 129-134
Skrzycki M., Czeczot H., Barańczyk-Kuźma A., Mielczarek-Puta M., Chrzanowska A., Gajewska B., (2011) Evaluation of beta2-microglobuline expression level in gastrointestinal tract tumors due to usefulness as a reference gene in PCR metod, Pol. Merkur. Lek., 31 (181), 24-30
Gutowicz M., Wpływ reaktywnych form tlenu na ośrodkowy układ nerwowy, Post. Hig. Med. Dosw., 2011, 65, 104-113
Grosicka-Maciąg E., (2011) Biologiczne skutki stresu oksydacyjnego wywołanego działaniem pestycydów, Post. Hig. Med. Dosw., 65, 357-366
Cichosz G., Czeczot H., (2011) Tluszcz mlekowy-źródło antyoksydantów w diecie człowieka, Bromat. Chem. Toksykol., 44 (1), 8-16
Majewska M., Czeczot H., Skrzycki M., Podsiad M., (2011) Aktywność przeciwutleniająca flawonoidów wobec anionorodnika ponadtlenkowego w układzie modelowym in vitro, Bromat. Chem. Toksykol., 44 (1), 1-7
Kuźma-Kozakiewicz M., Usarek E., Ludolph A.C., Barańczyk-Kuźma A., Mice with mutation in dynein heavy chain 1 do not share the same tau expression pattern with mice with SOD1-related motor neuron disease, Neurochem. Res., 2011, 36 (6), 978-985
Majewska M., Skrzycki M., Podsiad M., Czeczot H., Evaluation of antioxidant potential of flavonoids: an in vitro study, Acta Pol. Pharm., 2011, 68 (4), 611-615
Chudy A., Gajewska B., Gutowicz M., Barańczyk-Kużma A., Białka transportu wewnętrznego: klasyfikacja, budowa i funkcje kinezy. Post. Hig. Med. Dosw., 2011, 65, 588-596
Grosicka-Maciąg E.,Kurpios-Piec D., Szumiło M.,Grzela T.,Rahden-Staroń I. Protective effect of N-acetyl-L-cysteine against maneb induced oxidative and apoptotic injury in Chinese hamster V79 cells, Food Chem. Toxicol., 2011, 49, 1020-1025
Gutowicz M., Augustyn A., Pyrzanowska J., Widy-Tyszkiewicz E., Barańczyk-Kuźma A., (2011) Wpływ wieku i suplementacji kurkuminą na skuteczność mechanizmów detoksykacyjnych w tkankach szczura, Med. Wet., 67 (1), 55-58
Gutowicz M., Kaźmierczak B., Barańczyk-Kuźma A. The influence of glutathione-dependent enzymes in human brain, Drug Alkohol Depend., 2011,113, 8-12
Skrzycki M., Majewska M., Czeczot H. Superoxide dismutase mRNA and protein level in human colorectal kancer, Cent. Eur. J. Biol., 2010, 5 (5), 590-599
Gutowicz M. (2010) Zmiany statusu antyoksydacyjnego w mózgu człowieka po zatruciu heroiną. Medycyna, Dydaktyka, Wychowanie. XLII (3), 26-27
Pyrzanowska J., Piechal A., Blecharz-Klin K., Gutowicz M., Barańczyk-Kuźma A., Widy-Tyszkiewicz E. The influence of long- term administration of Curcuma longa extract on antioxidant processes as well as on motor activity in aged rats, Pharmacol. Reports, 2010, 62, 92
Czeczot H., Ścibior-Bentkowska D., Skrzycki M., Podsiad M., Ocena poziomu peroksydacji lipidów w surowicy chorych z nowotworami przewodu pokarmowego, Wiad. Lek., 2010, LXIII, 3, 180-187
Janik P., Kalbarczyk A., Gutowicz M., Barańczyk-Kuźma A., Kwieciński H.The analysis of selected neurotransmitter concentrations in serum of patients with Tourette syndrome, Neurologia i Neurochirurgia Polska, 2010, 44 (3), 251-259
Czeczot H., Ścibior-Bentkowska D., Skrzycki M., Majewska M., Podsiad M. Poziom peroksydacji lipidów w nowotworach przewodu pokarmowego, Pol. Merkur. Lek., 2010, XXIV, 173, 310-314
Grosicka-Maciąg E., Kurpios-Piec D., Grzela T., Czeczot H., Skrzycki M., Podsiad M., Szumiło M., Rahden-Staroń I.Protective effect of N-acetylcysteine against disulfiram induced oxidative stress and apoptosis in V79 cells, Toxicol. Appl. Pharmacol., 2010, 248, 210-216
Rahden-Staroń I., Suchocki P., Czeczot H.Evaluation of mutagenic activity of the organo-selenium compound Salol by use of the Salmonella typhimurium assay, Mut. Res./Genetic Toxicol.Environ.Mutagen., 2010, 699, 44-46
Li C.Z., Koter M., Ye X., Zhou S.F., Chou W., Luo R., Gershon P.D. Widespread but Small-Scale Changes in the Structural and Dynamic Properties of Vaccinia Virus Poly(A) Polymerase upon Association with Its Processivity Factor in Solution, Biochemistry, 2010, 49(29), 6247-6262
Beresewicz M., Majewska M.,Makarewicz D.,Vayro Steven, Zabłocka B., Górecki D.C., Changes in the expression of insulin-like growth factor 1 variants in the postnatal brain development and in neonatal hypoxia-ischaemia, Int. J. Devl. Neurosci., 2009, 28(1), 91-97
Ścibior-Bentkowska D., Skrzycki M., Podsiad M., Czeczot H., Changes in glutathione enzymatic redox system in human gastrointestinal tract tumors, Arch. Med. Sci., 2009, 5 (4), 500-505
Czeczot H., Majewska M., Skrzycki M., Podsiad M., Aktywność enzymów GSH-zależnych w surowicy krwi chorych z ostrym i przewlekłym zapaleniem trzustki, Wiad. Lek., 2009, 62(2), 87-92
Skrzycki M., Majewska M., Podsiad M., Czeczot H., Expression and activity of superoxide dismutase isoenzymes in colorectal cancer, Acta Biochim. Polon., 2009, 56(4), 663-670
Ścibior-Bentkowska D., Czeczot H., Komórki nowotworowe a stres oksydacyjny, Post. Hig.Med. Dosw., 2009, 63(1), 58-72
Chrzanowska A., Gajewska B., Barańczyk-Kuźma A., Arginase isoenzymes in human cirrhotic liver, Acta Biochim. Polon., 2009, 56(3), 465-469
Graboń W., Mielczarek-Puta M., Chrzanowska A., Barańczyk-Kuźma A., L-arginine as a factor increasing arginase significance in diagnosis of primary and metastatic colorectal cancer, Clin. Biochem., 2009, 42, 353-357